Educational information only — not medical advice. Most peptides here are not FDA-approved.
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BPC-157 + TB-500

The 'Wolverine stack' in one vial: local and whole-body repair together.

Not FDA-approvedWADA bannedEvidence

Overview

A premixed vial of BPC-157 and TB-500, the most popular recovery pairing. The idea is BPC-157 for local repair and TB-500 for body-wide recovery. Both are backed mostly by animal studies, and the combination itself has never been studied.

How it works

BPC-157 appears to boost growth-factor signaling and new blood vessels at injury sites. TB-500 binds actin and helps cells move into damaged tissue. They act on different pathways, which is the rationale for pairing them.

Evidence

2/5

No studies of the combination. Each part is mostly animal data with minimal human work.

Half-life

Short for both; dosed daily by convention

Known as

Wolverine stack, BPC/TB blend

Compound facts

Type
Synthetic pentadecapeptide
CAS Number
137525-51-0
Molecular Weight
1,419.5 g/mol
Amino Acids
15
Sequence
GEPPPGKPADDAGLV
Origin
Human gastric juice

Reported benefits

Animal

Tendon / ligament healing

BPC-157 sped tendon and ligament healing in rats.

Animal

Soft-tissue recovery

TB-500/thymosin beta-4 sped muscle and wound repair in animals.

Anecdotal

Faster return to training

The main reason people run it. Results are self-reported.

“Anecdotal” means reported by users, not shown in controlled trials.

Community-reported regimens

Not recommendations. These are commonly cited ranges, shown so you can see what real-world use looks like.

PlanDoseFrequencyDurationRoute
Community standard

Dose is of the total blend. At an equal split, 500 mcg gives about 250 mcg of each. Check the vial label for the split.

500 mcgOnce daily4–6 weeksSubcutaneous
Community higher

About 500 mcg of each at an equal split. Take 2–4 weeks off after.

1000 mcgOnce daily4–6 weeksSubcutaneous

Reconstitution calculator

Set up for BPC-157 + TB-500. Switch peptide or vial size any time.

Vial

1Mix

Bac water30 mL123mLBPC-157TB-50010 mg5 mg/mL

Add 2 mL water for 5 mg/mL

2Draw

051015202530U-100 · 0.3 mL10 units

Draw to 10 units = 0.1 mL = 500 mcg

Drag the plunger to set your dose.

3Inject

RL

Next site

Right belly, upper

Tap a site after you inject to keep a rotation.

Pinch the skin, stay 2 in. from the navel, then into a sharps bin.

Community doses:
Doses per vial
20
Vial lasts
20 days
Good once mixed
~28 days
Syringe
30-unit, 0.3 mL
Easier numbers, add this much water:

Math only: concentration (mg/mL) = vial mg ÷ mL of water; units = dose (mg) ÷ concentration × 100. Always double-check against your own vial label and a clinician. This tool does not recommend a dose.

Reconstitution

Diluent: Bacteriostatic water (0.9% benzyl alcohol) — allows multiple draws from one vial.

  1. Wipe both vial tops with an alcohol swab and let dry.
  2. Draw the diluent, then inject it slowly down the inside wall of the vial — never straight onto the powder.
  3. Swirl gently or let it sit; do not shake. Foam can damage peptides.
  4. Solution should be clear. Cloudy, stringy or discolored = discard.
  5. This is a blend. The dose you enter is total blend; at an equal split, half is BPC-157 and half TB-500.
  6. Common mix: 10 mg + 2 mL = 5 mg/mL (500 mcg = 10 units).

Full reconstitution guide →

Storage

Powder

Freezer / fridge

Keep sealed vial in the freezer (−20 °C) for long-term storage; fridge (2–8 °C) is fine for a few weeks. Keep dry and out of light.

After mixing

~28 days

Refrigerate at 2–8 °C. Never freeze after mixing. Keep upright, capped, and out of light.

Travel

Keep cool

Short trips at room temperature are generally fine for powder; keep mixed vials cold.

  • A ready-made nasal spray version is also sold. Nasal absorption of these peptides has not been studied in humans.

Side effects & cautions

Reported side effects

  • Injection-site redness or itch
  • Head rush or lightheadedness
  • Tiredness
  • Mild nausea
  • Unknown long-term effects

Cautions

  • Both components are banned by WADA.
  • Both promote blood-vessel growth or cell migration. That is a theoretical concern with a cancer history.
  • A fixed blend gives TB-500 daily rather than its usual twice-weekly schedule.
  • No data in pregnancy or breastfeeding.

Often paired with

GHK-Cu

Adding GHK-Cu for skin and collagen makes it the GLOW combination. No studies of the trio.

Where to buy

BPC-157 + TB-500 vials

SizePricePer mgStockLatest COA
10 mg$79.99$8.00In stock99.52% pure, lot WLV0003

ILS Labs, tested 2026-07-30

20 mg$149.99$7.50In stock99.68% pure, lot WLV0004

ILS Labs, tested 2026-07-30

Past COAs (4 lab reports)
  • 2026-07-30, 10 mg, lot WLV0003, 99.52% pure, measured 10.63mgILS Labs, passedView PDF
  • 2026-07-30, 20 mg, lot WLV0004, 99.68% pure, measured 21.39mgILS Labs, passedView PDF
  • 2026-05-29, 10 mg, lot WLV0001, 99.73% pure, measured 10.43mgILS Labs, passedView PDF
  • 2026-05-29, 20 mg, lot WLV0002, 99.67% pure, measured 20.54mgILS Labs, passedView PDF

BPC-157 + TB-500 nasal spray (ready-made)

View ↗
SizePricePer mgStockLatest COA
30 mg$99.99$3.33In stock99.19% pure, lot SWLV0001

ILS Labs, tested 2026-08-20

Past COAs (2 lab reports)
  • 2026-08-20, 30 mg, lot SWLV0001, 99.19% pure, measured 30.59mgILS Labs, passedView PDF
  • 2026-08-20, 30 mg, lot SWLV0001, measured 30.6 / 30.5mgEthos Analytical, passedView PDF

Amino Club list prices as of 2026-10-07, before promo codes. Multi-buy: 2+ units 5% off, 3+ units 7.5% off, 10+ units 40% off. Prices change; confirm on the product page. Mixing? Their bacteriostatic water is Amino H2O from $19.99.

BPC-157 + TB-500 at Amino Club

Check sizes, current price and the certificate of analysis (COA) on the product page. Sold for in-vitro research only.

Shop BPC-157 + TB-500 ↗

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  • Look for a batch-specific COA with HPLC purity (≥98%) and mass-spec identity.
  • Typical vial sizes: 10, 20 mg.

FAQ

Blend or two separate vials?

Separate vials let you dose BPC-157 daily and TB-500 twice weekly, the usual pattern. The blend is simpler but fixes the ratio.

Why is it called the Wolverine stack?

It's community slang for the hoped-for fast healing. It's a nickname, not a claim backed by studies.

Does the nasal spray work as well?

Unknown. There is no human data on nasal absorption of either peptide.

Read the primary research on PubMed ↗