DSIP
Sleep-promoting peptide first isolated from rabbit brain in the 1970s.
Overview
A nonapeptide that induced delta-wave sleep in early rabbit studies. Human trials are small and inconsistent. Used by some for sleep and stress, but the evidence is weak.
How it works
Poorly understood; modulates stress hormones and sleep architecture. Short half-life.
Evidence
2/5
Mixed small human trials from the 1980s–90s; no modern RCTs.
Half-life
About 7–8 minutes
Known as
Delta Sleep-Inducing Peptide
Compound facts
- Type
- Synthetic nonapeptide
- CAS Number
- 62568-57-4
- Molecular Formula
- C35H48N10O15
- Molecular Weight
- 848.8 g/mol
- Amino Acids
- 9 residues
- Sequence
- Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu
Reported benefits
Sleep onset
Some small studies in insomnia; results inconsistent.
Stress / withdrawal effects
Early studies in alcohol and opioid withdrawal.
“Anecdotal” means reported by users, not shown in controlled trials.
Community-reported regimens
Not recommendations. These are commonly cited ranges, shown so you can see what real-world use looks like.
| Plan | Dose | Frequency | Duration | Route |
|---|---|---|---|---|
| Community Range 100–300 mcg. | 200 mcg | Once, 30–60 min before bed | 2–3 weeks cycles | Subcutaneous |
Reconstitution calculator
Set up for DSIP. Switch peptide or vial size any time.
1Mix
Add 2 mL water for 2.5 mg/mL
2Draw
Draw to 8 units = 0.08 mL = 200 mcg
Drag the plunger to set your dose.
3Inject
Next site
Right belly, upper
Tap a site after you inject to keep a rotation.
Pinch the skin, stay 2 in. from the navel, then into a sharps bin.
- Doses per vial
- 25
- Vial lasts
- 35 days
- Good once mixed
- ~14 days
- Syringe
- 30-unit, 0.3 mL
The vial outlasts its ~14-day shelf life once mixed. A smaller vial wastes less.
Math only: concentration (mg/mL) = vial mg ÷ mL of water; units = dose (mg) ÷ concentration × 100. Always double-check against your own vial label and a clinician. This tool does not recommend a dose.
Reconstitution
Diluent: Bacteriostatic water (0.9% benzyl alcohol) — allows multiple draws from one vial.
- Wipe both vial tops with an alcohol swab and let dry.
- Draw the diluent, then inject it slowly down the inside wall of the vial — never straight onto the powder.
- Swirl gently or let it sit; do not shake. Foam can damage peptides.
- Solution should be clear. Cloudy, stringy or discolored = discard.
- Common mix: 5 mg + 2.5 mL = 2 mg/mL (200 mcg = 10 units).
Storage
Powder
Freezer / fridge
Keep sealed vial in the freezer (−20 °C) for long-term storage; fridge (2–8 °C) is fine for a few weeks. Keep dry and out of light.
After mixing
~14 days
Refrigerate at 2–8 °C. Never freeze after mixing. Keep upright, capped, and out of light.
Travel
Keep cool
Short trips at room temperature are generally fine for powder; keep mixed vials cold.
Side effects & cautions
Reported side effects
- Grogginess next morning
- Headache
- Vivid dreams
Cautions
- Avoid driving after dosing.
- Weak evidence — consider proven sleep strategies first.
FDA & international status
Not FDA-approved
Never approved by the FDA. Sold for research use.
Regulations change often — verify with the FDA, EMA, MHRA, Health Canada, TGA and WADA before acting.
Where to buy
DSIP vials
| Size | Price | Per mg | Stock | Latest COA |
|---|---|---|---|---|
| 5 mg | $29.99 | $6.00 | In stock | 99.45% pure, lot DSP0001 ILS Labs, tested 2026-07-30 |
DSIP nasal spray (ready-made)
View ↗| Size | Price | Per mg | Stock | Latest COA |
|---|---|---|---|---|
| 15 mg | $59.99 | $4.00 | Out of stock | 99.26% pure, lot SDSP0001 ILS Labs, tested 2026-08-20 |
Amino Club list prices as of 2026-10-07, before promo codes. Multi-buy: 2+ units 5% off, 3+ units 7.5% off, 10+ units 40% off. Prices change; confirm on the product page. Mixing? Their bacteriostatic water is Amino H2O from $19.99.
DSIP at Amino Club
Check sizes, current price and the certificate of analysis (COA) on the product page. Sold for in-vitro research only.
Get DSIP alerts
An email when its price drops, a sale starts, or its FDA or WADA status changes.
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- Look for a batch-specific COA with HPLC purity (≥98%) and mass-spec identity.
- Typical vial sizes: 2, 5, 10 mg.
FAQ
Is it a sedative?
Not in the usual sense. Studies describe sleep-promoting rather than sedating action, but results are inconsistent.